产品货号：
Z18030
中文名称：
INPP4B抗体
英文名称：
Anti-INPP4B Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-INPP4B Antibody |
| 指标别名 | Inositol polyphosphate-4-phosphatase type II 105kDa |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | INPP4B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | INPP4B antibody was raised against a 17 amino acid peptide near the amino terminus of human INPP4B.The immunogen is located within the last 50 amino acids of INPP4B. |
| 成分 | INPP4B antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | INPP4B antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Inositol polyphosphate 4-phosphatase type II (INPP4B) is one of the enzymes involved in phosphatidylinositol signaling pathways.It removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate (1).INPP4B can function as a tumor suppressor by inhibiting PI3K signaling.In human epithelial cells,knockdown of INPP4B expression resulted in enhanced Akt activation,anchorage-independent growth,and enhanced overall motility (2).It is thought INPP4B may also have oncogenic functions as INPP4B-dependent PI3K signaling is mediated by SGK3 in breast cancer cells and expression of INPP4B leads to enhanced SGK3 activation and suppression of AKT phosphorylation (3). |
| Uniprot ID | Q9BS68 |
| 基因名全称 | Inositol polyphosphate-4-phosphatase,type II,105kDa |
| 蛋白名全称 | Inositol polyphosphate-4-phosphatase,type II,105kDa |
| 推荐稀释比 | INPP4B antibody can be used for detection of INPP4B by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in mouse samples and Immunocytochemistry in mouse samples.All other applications and species not yet tested. |
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